Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder
Identifieur interne : 002214 ( Main/Exploration ); précédent : 002213; suivant : 002215Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder
Auteurs : Heike Stockner [Autriche] ; Alex Iranzo [Espagne] ; Klaus Seppi [Autriche] ; M Nica Serradell [Espagne] ; Viola Gschliesser [Autriche] ; Martin Sojer [Autriche] ; Francesc Valldeoriola [Espagne] ; José L. Molinuevo [Espagne] ; Birgit Frauscher [Autriche] ; Christof Schmidauer [Autriche] ; Joan Santamaria [Espagne] ; Birgit Högl [Autriche] ; Eduardo Tolosa [Espagne] ; Werner Poewe [Autriche]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-10-15.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Behavior, Case-Control Studies, Cohort Studies, Cross-Cultural Comparison, Female, Humans, Idiopathic, International Cooperation, Locus niger, Male, Mesencephalon (pathology), Mesencephalon (ultrasonography), Midbrain, Middle Aged, Nervous system diseases, Parkinson Disease (etiology), Parkinson Disease (ultrasonography), Parkinson disease, Parkinson's disease, Psychiatric Status Rating Scales, REM Sleep Behavior Disorder (complications), REM Sleep Behavior Disorder (pathology), REM Sleep Behavior Disorder (ultrasonography), Rapid eye movement sleep, Sleep disorder, Sonography, Ultrasonography, Doppler, Transcranial (methods), hyperechogenicity, idiopathic RBD, substantia nigra, transcranial sonography.
- MESH :
- complications : REM Sleep Behavior Disorder.
- etiology : Parkinson Disease.
- methods : Ultrasonography, Doppler, Transcranial.
- pathology : Mesencephalon, REM Sleep Behavior Disorder.
- ultrasonography : Mesencephalon, Parkinson Disease, REM Sleep Behavior Disorder.
- Aged, Case-Control Studies, Cohort Studies, Cross-Cultural Comparison, Female, Humans, International Cooperation, Male, Middle Aged, Psychiatric Status Rating Scales.
Abstract
Recent studies have reported an increased risk to develop Parkinson's disease (PD) in patients with idiopathic RBD (iRBD). Midbrain hyperechogenicity is a common transcranial sonography (TCS) finding in PD and has been suggested as a PD risk‐marker in nonparkinsonian subjects. The objective of this study is to assess midbrain echogenicity by TCS in patients with iRBD and compare the findings with the healthy controls. TCS was performed in 55 iRBD patients and in 165 age and sex‐matched controls. The area of echogenicity in the SN region in the iRBD group was significantly increased compared with the control group (P < 0.001). About 19 (37.3%) of patients with iRBD were found to have SN hyperechogenicity when compared with 16 (10.7%) of the controls (P < 0.001). This is the first case‐control study assessing midbrain echogenicity in a large iRBD cohort compared to age‐ and sex‐matched healthy individuals. The finding of an increased prevalence of hyperechogenicity in a subgroup of individuals with a priori increased risk for PD supports the potential role of hyperechogenicity as a risk marker for PD. The prospective follow‐up of this iRBD cohort is needed to establish if those with midbrain hyperechogenicity will go on to develop clinically defined PD or not. © 2009 Movement Disorder Society
Url:
DOI: 10.1002/mds.22483
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 002975
- to stream Istex, to step Curation: 002975
- to stream Istex, to step Checkpoint: 000E16
- to stream PubMed, to step Corpus: 001C15
- to stream PubMed, to step Curation: 001C15
- to stream PubMed, to step Checkpoint: 001D21
- to stream Ncbi, to step Merge: 002762
- to stream Ncbi, to step Curation: 002762
- to stream Ncbi, to step Checkpoint: 002762
- to stream Main, to step Merge: 002A75
- to stream PascalFrancis, to step Corpus: 000D50
- to stream PascalFrancis, to step Curation: 001F69
- to stream PascalFrancis, to step Checkpoint: 000E10
- to stream Main, to step Merge: 002F07
- to stream Main, to step Curation: 002214
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder</title><author><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name></author><author><name sortKey="Iranzo, Alex" sort="Iranzo, Alex" uniqKey="Iranzo A" first="Alex" last="Iranzo">Alex Iranzo</name></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name></author><author><name sortKey="Serradell, M Nica" sort="Serradell, M Nica" uniqKey="Serradell M" first="M Nica" last="Serradell">M Nica Serradell</name></author><author><name sortKey="Gschliesser, Viola" sort="Gschliesser, Viola" uniqKey="Gschliesser V" first="Viola" last="Gschliesser">Viola Gschliesser</name></author><author><name sortKey="Sojer, Martin" sort="Sojer, Martin" uniqKey="Sojer M" first="Martin" last="Sojer">Martin Sojer</name></author><author><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name></author><author><name sortKey="Molinuevo, Jose L" sort="Molinuevo, Jose L" uniqKey="Molinuevo J" first="José L." last="Molinuevo">José L. Molinuevo</name></author><author><name sortKey="Frauscher, Birgit" sort="Frauscher, Birgit" uniqKey="Frauscher B" first="Birgit" last="Frauscher">Birgit Frauscher</name></author><author><name sortKey="Schmidauer, Christof" sort="Schmidauer, Christof" uniqKey="Schmidauer C" first="Christof" last="Schmidauer">Christof Schmidauer</name></author><author><name sortKey="Santamaria, Joan" sort="Santamaria, Joan" uniqKey="Santamaria J" first="Joan" last="Santamaria">Joan Santamaria</name></author><author><name sortKey="Hogl, Birgit" sort="Hogl, Birgit" uniqKey="Hogl B" first="Birgit" last="Högl">Birgit Högl</name></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation><country>Autriche</country><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:9F02785EF04BBFC66626CE7067E959932C00F521</idno><date when="2009" year="2009">2009</date><idno type="doi">10.1002/mds.22483</idno><idno type="url">https://api.istex.fr/document/9F02785EF04BBFC66626CE7067E959932C00F521/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002975</idno><idno type="wicri:Area/Istex/Curation">002975</idno><idno type="wicri:Area/Istex/Checkpoint">000E16</idno><idno type="wicri:doubleKey">0885-3185:2009:Stockner H:midbrain:hyperechogenicity:in</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:19645057</idno><idno type="wicri:Area/PubMed/Corpus">001C15</idno><idno type="wicri:Area/PubMed/Curation">001C15</idno><idno type="wicri:Area/PubMed/Checkpoint">001D21</idno><idno type="wicri:Area/Ncbi/Merge">002762</idno><idno type="wicri:Area/Ncbi/Curation">002762</idno><idno type="wicri:Area/Ncbi/Checkpoint">002762</idno><idno type="wicri:Area/Main/Merge">002A75</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:09-0472205</idno><idno type="wicri:Area/PascalFrancis/Corpus">000D50</idno><idno type="wicri:Area/PascalFrancis/Curation">001F69</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000E10</idno><idno type="wicri:doubleKey">0885-3185:2009:Stockner H:midbrain:hyperechogenicity:in</idno><idno type="wicri:Area/Main/Merge">002F07</idno><idno type="wicri:Area/Main/Curation">002214</idno><idno type="wicri:Area/Main/Exploration">002214</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder</title><author><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Iranzo, Alex" sort="Iranzo, Alex" uniqKey="Iranzo A" first="Alex" last="Iranzo">Alex Iranzo</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Serradell, M Nica" sort="Serradell, M Nica" uniqKey="Serradell M" first="M Nica" last="Serradell">M Nica Serradell</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Gschliesser, Viola" sort="Gschliesser, Viola" uniqKey="Gschliesser V" first="Viola" last="Gschliesser">Viola Gschliesser</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Sojer, Martin" sort="Sojer, Martin" uniqKey="Sojer M" first="Martin" last="Sojer">Martin Sojer</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Molinuevo, Jose L" sort="Molinuevo, Jose L" uniqKey="Molinuevo J" first="José L." last="Molinuevo">José L. Molinuevo</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Frauscher, Birgit" sort="Frauscher, Birgit" uniqKey="Frauscher B" first="Birgit" last="Frauscher">Birgit Frauscher</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Schmidauer, Christof" sort="Schmidauer, Christof" uniqKey="Schmidauer C" first="Christof" last="Schmidauer">Christof Schmidauer</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Santamaria, Joan" sort="Santamaria, Joan" uniqKey="Santamaria J" first="Joan" last="Santamaria">Joan Santamaria</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Hogl, Birgit" sort="Hogl, Birgit" uniqKey="Hogl B" first="Birgit" last="Högl">Birgit Högl</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion></affiliation></author><author><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><affiliation wicri:level="3"><country xml:lang="fr">Espagne</country><wicri:regionArea>Neurology Service, Hospital Clinic de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><affiliation wicri:level="1"><country xml:lang="fr">Autriche</country><wicri:regionArea>Department of Neurology, Medical University Innsbruck, Innsbruck</wicri:regionArea><wicri:noRegion>Innsbruck</wicri:noRegion><placeName><settlement type="city">Innsbruck</settlement><region nuts="2" type="region">Tyrol (Land)</region></placeName><orgName type="university">Université de médecine d'Innsbruck</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2009-10-15">2009-10-15</date><biblScope unit="vol">24</biblScope><biblScope unit="issue">13</biblScope><biblScope unit="page" from="1906">1906</biblScope><biblScope unit="page" to="1909">1909</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">9F02785EF04BBFC66626CE7067E959932C00F521</idno><idno type="DOI">10.1002/mds.22483</idno><idno type="ArticleID">MDS22483</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Behavior</term><term>Case-Control Studies</term><term>Cohort Studies</term><term>Cross-Cultural Comparison</term><term>Female</term><term>Humans</term><term>Idiopathic</term><term>International Cooperation</term><term>Locus niger</term><term>Male</term><term>Mesencephalon (pathology)</term><term>Mesencephalon (ultrasonography)</term><term>Midbrain</term><term>Middle Aged</term><term>Nervous system diseases</term><term>Parkinson Disease (etiology)</term><term>Parkinson Disease (ultrasonography)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Psychiatric Status Rating Scales</term><term>REM Sleep Behavior Disorder (complications)</term><term>REM Sleep Behavior Disorder (pathology)</term><term>REM Sleep Behavior Disorder (ultrasonography)</term><term>Rapid eye movement sleep</term><term>Sleep disorder</term><term>Sonography</term><term>Ultrasonography, Doppler, Transcranial (methods)</term><term>hyperechogenicity</term><term>idiopathic RBD</term><term>substantia nigra</term><term>transcranial sonography</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Ultrasonography, Doppler, Transcranial</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Mesencephalon</term><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" qualifier="ultrasonography" xml:lang="en"><term>Mesencephalon</term><term>Parkinson Disease</term><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Cohort Studies</term><term>Cross-Cultural Comparison</term><term>Female</term><term>Humans</term><term>International Cooperation</term><term>Male</term><term>Middle Aged</term><term>Psychiatric Status Rating Scales</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Comportement</term><term>Exploration ultrason</term><term>Idiopathique</term><term>Locus niger</term><term>Maladie de Parkinson</term><term>Mésencéphale</term><term>Pathologie du système nerveux</term><term>Sommeil paradoxal</term><term>Trouble du sommeil</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Recent studies have reported an increased risk to develop Parkinson's disease (PD) in patients with idiopathic RBD (iRBD). Midbrain hyperechogenicity is a common transcranial sonography (TCS) finding in PD and has been suggested as a PD risk‐marker in nonparkinsonian subjects. The objective of this study is to assess midbrain echogenicity by TCS in patients with iRBD and compare the findings with the healthy controls. TCS was performed in 55 iRBD patients and in 165 age and sex‐matched controls. The area of echogenicity in the SN region in the iRBD group was significantly increased compared with the control group (P < 0.001). About 19 (37.3%) of patients with iRBD were found to have SN hyperechogenicity when compared with 16 (10.7%) of the controls (P < 0.001). This is the first case‐control study assessing midbrain echogenicity in a large iRBD cohort compared to age‐ and sex‐matched healthy individuals. The finding of an increased prevalence of hyperechogenicity in a subgroup of individuals with a priori increased risk for PD supports the potential role of hyperechogenicity as a risk marker for PD. The prospective follow‐up of this iRBD cohort is needed to establish if those with midbrain hyperechogenicity will go on to develop clinically defined PD or not. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Autriche</li><li>Espagne</li></country><region><li>Catalogne</li><li>Tyrol (Land)</li></region><settlement><li>Barcelone</li><li>Innsbruck</li></settlement><orgName><li>Université de médecine d'Innsbruck</li></orgName></list><tree><country name="Autriche"><noRegion><name sortKey="Stockner, Heike" sort="Stockner, Heike" uniqKey="Stockner H" first="Heike" last="Stockner">Heike Stockner</name></noRegion><name sortKey="Frauscher, Birgit" sort="Frauscher, Birgit" uniqKey="Frauscher B" first="Birgit" last="Frauscher">Birgit Frauscher</name><name sortKey="Gschliesser, Viola" sort="Gschliesser, Viola" uniqKey="Gschliesser V" first="Viola" last="Gschliesser">Viola Gschliesser</name><name sortKey="Hogl, Birgit" sort="Hogl, Birgit" uniqKey="Hogl B" first="Birgit" last="Högl">Birgit Högl</name><name sortKey="Poewe, Werner" sort="Poewe, Werner" uniqKey="Poewe W" first="Werner" last="Poewe">Werner Poewe</name><name sortKey="Schmidauer, Christof" sort="Schmidauer, Christof" uniqKey="Schmidauer C" first="Christof" last="Schmidauer">Christof Schmidauer</name><name sortKey="Seppi, Klaus" sort="Seppi, Klaus" uniqKey="Seppi K" first="Klaus" last="Seppi">Klaus Seppi</name><name sortKey="Sojer, Martin" sort="Sojer, Martin" uniqKey="Sojer M" first="Martin" last="Sojer">Martin Sojer</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Iranzo, Alex" sort="Iranzo, Alex" uniqKey="Iranzo A" first="Alex" last="Iranzo">Alex Iranzo</name></region><name sortKey="Molinuevo, Jose L" sort="Molinuevo, Jose L" uniqKey="Molinuevo J" first="José L." last="Molinuevo">José L. Molinuevo</name><name sortKey="Santamaria, Joan" sort="Santamaria, Joan" uniqKey="Santamaria J" first="Joan" last="Santamaria">Joan Santamaria</name><name sortKey="Serradell, M Nica" sort="Serradell, M Nica" uniqKey="Serradell M" first="M Nica" last="Serradell">M Nica Serradell</name><name sortKey="Tolosa, Eduardo" sort="Tolosa, Eduardo" uniqKey="Tolosa E" first="Eduardo" last="Tolosa">Eduardo Tolosa</name><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002214 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002214 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:9F02785EF04BBFC66626CE7067E959932C00F521
|texte= Midbrain hyperechogenicity in idiopathic REM sleep behavior disorder
}}
| This area was generated with Dilib version V0.6.23. |  |